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Interview with Michael T. Murray, ND - natural alternatives to Vioxx

Mike Adams, the Health Ranger
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Probably the most well documented product is glucosamine sulfate. It really addresses the underlying cause, that glucosamine is utilized by the body to manufacture cartilage components. Studies have shown that as people get older they lose the ability to manufacture sufficient quantities of glucosamine. So it's a virtual deficiency state. Giving them the glucosamine leads to growth and regeneration of the cartilage. That's good medicine. This addresses the cause with the solution. In addition to glucosamine sulfate, there are a number of other products that can be used and have documentation.

PDR for Herbal Medicines, Fourth Edition

Thomson Healthcare, Inc.
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Cohen M, Wolfe R, Mai T et al: A randomized, double blind, placebo controlled trial of a topical cream containing glucosamine sulfate, chondroitin sulfate, and camphor for osteoarthritis of the knee. J Rheumatol; 30(3):523-528. 2003 Conte A, de Bernardi M, Palmieri L et al: Metabolic fate of exogenous chondroitin sulfate in man. Arzneimittelforschung; 41(7):768-772. 1991 Leeb BF, Schweitzer H, Montag K et al: A meta-analysis of chondroitin sulfate in the treatment of osteoarthritis. J Rheumatol; 27(1):205-211.

Supplement Your Prescription: What Your Doctor Doesn't Know About Nutrition

Hyla Cass
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Glucosamine/chondroitin: 1,500 mg of glucosamine sulfate per day alone to start; if you don't discern any benefit within three months, try adding 1,200 mg of chondroitin daily ?MSM: Up to 6 grams daily ?Turmeric: 400-600 mg three times daily Don't forget to follow the diet and multivitamin recommendations from Chapter 2. All forms of arthritis respond well to natural treatments, including supplements. Most of these treatments are side-effect free, and they treat the problem at its root cause rather than simply addressing the symptoms.

What Your Doctor Doesn't Know About Nutritional Medicine May Be Killing You

Ray D. Strand
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She also started taking 2,000 mg of glucosamine sulfate. Peggie continued following her physical therapy guidelines and ate a balanced diet. Within a few months of beginning a nutritional supplement program, Peggie could already begin to feel and see improvement. She was less dependent on her NSAIDS and was now able to do more than she had for years. She became much more active and felt less pain. In fact she even overcame her fears and went snow skiing for the first time in years.
Early studies showed short-term benefits of the use of glucosamine sulfate; however, most physicians remained unimpressed.5 In 1999 a three-year, large, randomized-sample, placebo-controlled, double-blind clinical trial (the sort of studies doctors really like) was reported at the Annual Meeting of the American College of Rheumatology. This study showed that glucosamine not only reduced the pain and inflammation of arthritis but actually stopped the deterioration of the cartilage.
To the dismay of pharmaceutical companies, more and more physicians are recommending glucosamine sulfate to their patients. The results I have seen in my practice are impressive. Even though I recommend glucosamine to all my arthritis patients, I also prescribe NSAIDS for quick relief. It is exciting to discover my patients who decide to take glucosamine eventually hardly ever need to take their NSAIDS. When they are willing to add the antioxidants, minerals, essential fats, and grape-seed extract, they do even better. I'm not alone in my convictions.
I personally feel that the most important nutrient is still glucosamine sulfate. Oral chondroitin needs to be studied more thoroughly in larger number of patients, allowing more plausible evidence as to whether chondroitin is really a player or not. I also believe MSM (a natural anti-inflammatory) needs to be studied more thoroughly. But I have had several patients who experienced a significant response when they added it to their regime. Chondroitin Sulfate Several studies show improvement in patients with arthritis who are getting additional chondroitin.
Other optimizers would be CoQlO, glucosamine sulfate, lutein, zeaxanthine, niacin, magnesium, and calcium. Following are the basic principles and nutrients I use as optimizers in these various chronic degenerative diseases. All of my patients are taking the nutrients detailed in Table 1. I then add additional optimizers to this basic cellular nutrition program according to the seriousness of each individual case. Other than grape-seed extract, the optimizer I recommend most is CoQlO. It is not only a potent antioxidant but it is also essential for the creation of energy within the cell.
This study, along with several others, has shown the significant health benefit for arthritis patients who take glucosamine sulfate supplements in the 1,500-2,000-mg range, with virtually no side effects. Even more exciting is the fact that when the patients in the clinical trial discontinued their glucosamine, the pain did not return for weeks and even months later.7 NSAIDS, on the other hand, have significant side effects such as ulcers, upper GI bleeding, and possible liver damage, as I noted earlier.

Overcoming Arthritis

David Brownstein
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It is clear that glucosamine sulfate and chondroiten sulfate, instead of NSAIDS, should be the first line of treatment for any form of arthritis. Recommended Doses of glucosamine sulfate and Chondroiten Sulfate For arthritic conditions I recommend the following doses: glucosamine sulfate- 500 mg three times per day and chondroiten sulfate- 400mg three times per day. These supplements work best when used in combination, rather than individually. Herbs Herbs have been used in many different cultures to help control the symptoms of arthritis.

Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing

Jonathan V. Wright, M.D. and Alan R. Gaby, M.D.
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We usually recommend glucosamine sulfate for our patients, without the addition of chondroitin sulfate. However, we have no objection if someone wants to use the more expensive combination treatment. Vitamin E and Selenium Vitamin E has a mild anti-inflammatory effect, similar to that of aspirin-like drugs. Although vitamin E is not nearly as strong as aspirin and related drugs, it also doesn't produce any of the side effects associated with these drugs.
Glucosamine sulfate, 500 mg, 3 times a day. May use in combination with chondroitin sulfate, 800 to 1,200 mg per day. Other Recommendations: • Vitamin E, 400 to 800 IU per day. • Selenium, 100 to 200 meg per day. • Vitamin C, 500 to 1,000 mg, 2 times a day (to strengthen connective tissue). • Multiple vitamin/mineral (adjust doses of other nutrients according to the amounts in the multiple). • S-adenosylmethionine (SAMe), 400 to 600 mg per day, in selected cases, with medical super vision. Osteoporosis S>9' osteoporosis is defined as thin or porous bones.

Nature's Medicines : From Asthma to Weight Gain, from Colds to High Cholesterol -- The Most Powerful All-Natural Cures

Gale Maleskey
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While the label may state that NAG is better-utilized and therefore more effective than glucosamine sulfate, research has not yet been conducted that would prove or disprove that claim, says Dr. Aesoph. "The big argument now is what form to use," she explains. "We need studies where these different forms are compared head-to-head." In the meantime, glucosamine sulfate is the supplement of choice. "The bulk of the research is on glucosamine sulfate," says Dr. Aesoph, "so we know that works.

The Vitamin Revolution in Health Care

Michael Janson, M.D.
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When joints are inflamed from osteoarthritis (degenerative joint disease), supplements of glucosamine sulfate are often helpful in relieving symptoms and restoring joint integrity. glucosamine sulfate actually stimulates new cartilage formation to protect the bone surface. In fact, studies have shown that taking glucosamine sulfate is better than the usual drugs for arthritis, called nonsteroidal antiinflammatory drugs (or NSAIDS), like Motrin®, Indocin®, Advil®, and Naprosyn®.

Natural Medicine, Optimal Wellness: The Patient's Guide to Health and Healing

Jonathan V. Wright, M.D. and Alan R. Gaby, M.D.
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The slow but progressive improvement obtained with glucosamine sulfate suggests that this compound promotes healing of joints, rather than merely relieving symptoms. That possibility is supported by observations from one study, in which biopsies of osteoarthritic knees taken before and after 30 days of glucosamine-sulfate therapy revealed that degenerating tissue had been replaced by more healthy looking joint cartilage.9 Evidently, the commonly held belief that osteoarthritis is an irreversible disease is wrong.

Interview with Michael T. Murray, ND - natural alternatives to Vioxx

Mike Adams, the Health Ranger
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And like the glucosamine sulfate and MSM, there is some good documentation showing Celadrin to be both safe and effective in the treatment of osteoarthritis. And it's likely that Celadrin has many other applications because of this unique anti-inflammatory effect. Mike: And it has been shown to be effective topically? Dr. Murray: Yes, both orally and topically. Mike: That's interesting, because there is a lot of talk today about C-reactive proteins and inflammatory causative factors of heart disease and other diseases. So could Celadrin potentially have use there as well? Dr.

The New Optimum Nutrition Bible

Patrick Holford
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Glucosamine hydrochloride works better than glucosamine sulfate. Glucosamine is a major component of joint tissue and, as a supplement, works to stimulate joint function and repair. It is most effective in battling osteoarthritis, the most prevalent type of arthritis. A number of studies over the last twenty years have shown this. For example, a 1982 clinical study compared usage of the NSAID ibuprofen with that of glucosamine sulfate for osteoarthritis of the knee.

Integrative Medicine journal brings together conventional doctors, naturopaths, nutritionists, chiropractors and others in the healing arts: an interview with Dr. Joseph Pizzorno

Mike Adams, the Health Ranger
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Mike: And this is glucosamine sulfate, you said, vitamin C, lipoic acid? Dr. Pizzorno: Right. Mike: Those are the big three, huh? Dr. Pizzorno: Well, and other things. I also take more vitamin E, and carnitine. One of the challenges people have is that our mitochondria, which are, you might say, the energy producers in the cells, they wear out over time, and most people, by the time they hit 50, the mitochondria are pretty dysfunctional at that point, and they start going downhill pretty quickly. That's one reason why older people have less energy than young people.

Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements

Phyllis A. Balch, CNC
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Coenzyme-A Technologies Contains pantothenic acid, glucosamine sulfate, chondroitin sulfate, cerasomal-cis-9-cetylmyristoleate, methylfsul-fonylmethane (MSM), and other nutrients to support healthy bone, joint, ligament, and cartilage function. L-Cysteine 500 mg twice daily, on an empty stomach. Take with water or juice. Do not take with milk. Take with 50 mg vitamin B$ and 100 mg vitamin C for better absorption. A detoxifier essential for immune function; a source of sulfur and component of collagenous tissue. (See AMINO ACIDS in Part One.) L-Histidine As directed on label.
GlucosaMend from Source Naturals, Glucosamine Plus from FoodScience of Vermont, and glucosamine sulfate Complex from PhytoPharmica are other recommended products. A related compound is N-acetylglucosamine (NAG), available as N-A-G from Source Naturals. Grape Seed Oil See under Essential Fatty Acids in this section. "Green Drinks" "Green drinks" are natural food formulas made from plants that are good detoxifiers and blood cleansers, as well as sources of chlorophyll, minerals, enzymes, and other important nutrients. Generally, they are sold in powdered form to be mixed just before use.
It is also available as a supplement, in the form of glucosamine sulfate, which helps to combat both the causes and symptoms of osteoarthritis. Glucosamine has been proven in more than three hundred studies and twenty clinical trials to actually build joint cartilage. It can also slightly reduce the destruction of cartilage and depression caused by taking nonsteroidal antiinflammatory drugs (NSAIDs), which are commonly prescribed for people with arthritis.

Natural Alternatives to Vioxx, Celebrex and other Anti-Inflammatory Prescription Drugs

Carol Simontacchi
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The research performed on these natural anti-inflammatories includes the following: In a study of 414 women with osteoarthritis of the knee, women taking 1,500 mg of glucosamine sulfate (GS) daily experienced no further loss in cartilage tissue, while the placebo group continued to experience cartilage destruction. The women taking the GS supplement also experienced a reduction in pain and an improvement in function.

Anti-Aging Manual: The Encyclopedia of Natural Health

Joseph E. Mario
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Colostrum contains glucosamine sulfate, MethylSulfonylMethane (MSM), and Proline-Rich Polypeptide (PRP) that restoresthymus gland flmction,irihiDitsoveiproductionofT-celisandLymphocytes. Dose 2000-2,500 mg. twice daily on an empty stomach. •DEER ANTLER Velvet Called Lu Rong in China where it has been used 2000 years for circulation, building Red blood cells countering anemia; and empowering the kidneys, understood as an energy reserve for reproduction, growth, increases cell replication 300%, bui Ids the skeleton, lungs, and endocrine glands.

Healing Pets With Nature's Miracle Cures

Henry Pasternak, D.V.M., C.V.A.
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Most of the efficacious research shows that glucosamine sulfate in its stabilized form is efficacious in osteoarthritis; however, other forms lack the extensive studies to support their use.7 glucosamine sulfate by itself does not act as a pain reliever or anti-inflammatory; rather it acts by initiating repair of damaged joint tissue. I have been using stabilized glucosamine sulfate for a number of years with great success. Many products are not stabilized and thus lose their potency over time.

Natural Health Solutions

Mike Adams
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ArthroMax, Super Curcumin with Bioperine, glucosamine sulfate, Chondroitin Sulfate, Super EPA / DHA with Sesame Lignans and Olive Fruit Extract (www.LEF.org) *" Joint Support Liquid Concentrate (www.Eidon.com) Hyaluronic Acid (www.WellnessResources.com) Kidney stones Like most other diseases and conditions mentioned here, kidney stones are also preventable. What causes kidney stones? The short answer is: Drinking soft drinks, coffee, and lots of tea. Kidney stones are formed through a variety of biochemical processes, but those are the primary foods and beverages that cause kidney stones.

Interview with Michael T. Murray, ND - natural alternatives to Vioxx

Mike Adams, the Health Ranger
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In addition to glucosamine sulfate, there are a number of other products that can be used and have documentation. For example, MSM is a physiological form of sulfur that has been shown to enhance the effectiveness of glucosamine. Sulfur is most likely utilized in the manufacture of these cartilage components as well. Mike: What about Celadrin? Dr. Murray: Celadrin is a new product that has just hit the market. It's been shown in studies to be effective both topically and orally.

The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions

Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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To make it easier, our doctors recommend trying these simple steps first: Help prevent joint damage with GS and CS Take 1,500 mg a day of glucosamine sulfate, 800 to 1,200 mg a day of chondroitin sulfate, or a combination of the two, for pain and to protect joints Use topical capsaicin Treat discomfort with an ointment or cream containing 0.025 to 0.

The Encyclopedia of Healing Foods

by Michael Murray, N.D. and Joseph Pizzorno, N.D.
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The more than twenty published clinical trials with glucosamine sulfate have demonstrated an overall success rate of 72 to 95 percent in various forms of OA. In OA of the knee, the success rate is more than 80 percent.

Prescription for Natural Cures: A Self-Care Guide for Treating Health Problems with Natural Remedies Including Diet and Nutrition, Nutritional Supplements, Bodywork, and More

James F. Balch, M.D. and Mark Stengler, N.D.
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People who are allergic to sulfa drugs do not need to be concerned as the source of the drugs is different from the mineral sulfur that is part of glucosamine sulfate. Dosage: Take 1,500 mg daily. Glutamic Acid Description: Glutamic acid is an amino acid that is suited to build protein arid has been studied for the symptoms of prostate enlargement. Indications: Prostate enlargement Precautions: People with liver or kidney disease should not supplement amino acids unless under the direction of a health-care professional.

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